Simultaneous estimation of metformin and pioglitazone by ultraviolet spectrophotometry
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چکیده
منابع مشابه
Simultaneous Estimation of Metformin and Pioglitazone by Ultraviolet Spectrophotometry
This work deals with the simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in a bilayered tablet dosage form, without prior separation by two techniques. The methods employed are derivative spectrophotometery and Q analysis. The absorption maxima at 231 nm and 269 nm were used for the estimation of metformin and pioglitazone, respectively. Both the drugs and thei...
متن کاملSimultaneous Determination of Barbiturates and Salicylates by Ultraviolet Spectrophotometry.
A rapid method based on UV spectrophotometry is described for simultaneous determination of salicylates and barbiturates in serum. While barbiturates have no absorbance above 280 m and extracted normal serum has insignificant absorbance, salicylate has a maximal absorbance peak at 296 mjh, which is proportional to concentration. The barbiturate concentration can be calculated from absorbance di...
متن کاملSimultaneous Estimation of Metformin Hydrochloride and Pioglitazone Hydrochloride by RPHPLC Method from Combined Tablet Dosage Form
A high performance reverse phase liquid chromatographic procedure is developed for simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in combined tablet dosage form. The mobile phase used was a combination of acetonitrile:water:acetic acid (60:40:0.3) and the pH was adjusted to 5.5 by adding triethylamine. The detection of the combined dosage form was carried out ...
متن کاملSimultaneous determination and pharmacokinetic study of metformin and pioglitazone in dog plasma by LC-MS-MS.
A high-performance liquid chromatography-tandem mass spectrometry method was developed for the simultaneous determination of metformin (MET) and pioglitazone (PIO) in dogs. To increase the reliability of the method, moroxydine (IS-1) and rosiglitazone (IS-2) were used as internal standards for MET and PIO, respectively. The analytes were extracted from beagle dog plasma by a one-step protein pr...
متن کاملSimultaneous determination of moxifloxacin and cefixime by first and ratio first derivative ultraviolet spectrophotometry
UNLABELLED BACKGROUND The new combination of moxifloxacin HCl and cefixime trihydrate is approved for the treatment of lower respiratory tract infections in adults. At initial formulation development and screening stage a fast and reliable method for the dissolution and release testing of moxifloxacin and cefixime were highly desirable. The zero order overlaid UV spectra of moxifloxacin and ...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2010
ISSN: 0250-474X
DOI: 10.4103/0250-474x.73940